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化学与生命健康交叉研究中心

陈世贵
时间:2022-03-09 11:31:04点击量:

陈世贵

教授,博士生导师

邮箱:sgchen@whu.edu.cn

课题组主页:https://www.x-mol.com/groups/chen_shigui

研究方向

1. 超分子药物体系:基于分子识别体系,发展针对特定毒物、药物的超分子拮抗剂;基于超分子组装,发展复合药物载体。

2. 超分子材料:新型框架结构(XOF)的构建与应用;基于自组装构建响应型超分子材料;智能光电响应材料/器件的研究及应用

导师介绍

教育与工作经历

2017.01-至今 金沙8888js,教授

2012.01-2016.12美国俄亥俄州立大学博士后,导师:Prof. Jovica D. Badjić

2011.01-2011.12中国科学院上海有机化学研究所研究助理,导师:黎占亭、赵新研究员

2005.09-2010.12中国科学院上海有机化学研究所博士,导师:蒋锡夔院士、黎占亭研究员

2001.09-2005.07南开大学,材料化学,理学学士

代表性论文

(13) Gong, G. F. [+]; Lv, S. H. [+]; Han, J. X.; Xie, F.; Li, Q.; Xia, N.; Zeng, W.; Chen, Y.; Wang, L.; Wang, J. K.*; Chen, S. G.*, Halogen-Bonded Organic Framework (XOF) Based on Iodonium-Bridged N···I+···N Interactions: A Type of Diphase Periodic Organic Network, Angew. Chem. Int. Ed. 2021, 14831-14835. (Hot paper)

(12) Zhou, S. [+]; Li, W. [+]; Zhao, Q.; Dong, H.; Wang, Y.; Lu, F.; Zhao, J.; Liu, S.; Chen, H.; Wang, L.; Liu, W.*; Zhang, M.*; Chen, S. G.*, Detoxification of the Toxic Sulfur Mustard Simulant by a Supramolecular Antidote in Vitro and in Vivo, ACS Appl. Mater. Interfaces 2021, 13, 58291-58300.

(11) Ju, B. H.; Chen, S. G.*; Kong, W. Q.*, Enantioselective palladium-catalyzed diarylation of unactivated alkenes, Chem. Commun. 2019, 55, 14311-14314.

(10) Ju, B. H.; Chen, S. G.*; Kong, W. Q.*, Pd-Catalyzed Enantioselective Double Heck Reaction, Org. Lett. 2019, 21, 9343-9347.

(9) Wang, L. , Neal, T.; Chen, S. G.*; Badjić, J. D.*, Multivalent and Photoresponsive Assembly of Dual-Cavity Baskets in Water, Chem. Eur. J. 2017, 23, 8829-8833.

(8) Chen, S. G. [+]; Wang, L. [+], Polen, S.; Badjić, J. D.*, On Gating the Trafficking of Molecules across Vesicular Membrane Composed of Dual-Cavity Baskets. Chem. Mater. 2016, 28, 8128–8131. ( [+] These authors contributed equally to this project.)

(7) Chen, S. G.; Polen, S.; Wang, L., Yamasaki, M.; Hadad, C. M.; Badjić, J. D.*, On Two-Dimensional Supramolecular Polymers Embodying Large Unilamellar Vesicles in Water. J. Am. Chem. Soc. 2016, 138, 11312-11317.

(6) Chen, S. G., Zhao, Z. X., Jiang, X. N., Wang, L., Zhou, T. Y., Lu, C. L., Zhao, X.,*, Jiang, X. K., Ma, Y. G.,* Wang, R. X.,* Li, Z. T.*, Temperature-Responsive Chiral (A)6B Supramolecular Cages Based on Conformational Preferences, Chem.-Asian J. 2016, 11, 465−469.

(5) Chen, S. G.; Yamasaki, M.; Polen, S.; Gallucci, J.; Hadad, C. M.; Badjić, J. D.*, Dual-Cavity Baskets Promote Encapsulation in Water in an Allosteric Fashion. J. Am. Chem. Soc. 2015, 137, 12276−12281.

(4) Chen, S. G.; Ruan, Y.; Brown, J. D.; Hadad, C. M.; Badjić, J. D.*, The Recognition Characteristics of Adaptive Assemblies of Amphiphilic Baskets for Selective Detection and Mitigation of Toxic Nerve Agents. J. Am. Chem. Soc. 2014, 136, 17337–17342.

(3) Chen, S. G.; Ruan, Y.; Brown, J. D.; Gallucci, J.; Maslak, V.; Hadad, C. M.; Badjić, J. D.*, Assembly of Amphiphilic Baskets into Stimuli-Responsive Vesicles. Developing a Strategy for the Detection of Organophosphorus Chemical Nerve Agents. J. Am. Chem. Soc. 2013, 135, 14964-14967.

(2) You, L. Y. [+]; Chen, S. G.[+]; Zhao, X.*; Liu, Y.; Lan, W. X.; Zhang, Y.; Lu, H. J.; Cao, C. Y.; Li, Z. T.*, C‒H•••O Hydrogen Bonding Induced Triazole Foldamers: Efficient Halogen Bonding Receptors for Organohalogens. Angew. Chem. Int. Edit. 2012, 51, 1657-1661.( [+] These authors contributed equally to this project.)

(1) Chen, S. G.; Yu, Y.; Zhao, X.*; Ma, Y. G.*; Jiang, X. K.; Li, Z. T.*, Highly Stable Chiral (A)6-B Supramolecular Copolymers: A Multivalency-Based Self-Assembly Process. J. Am. Chem. Soc. 2011, 133, 11124 -11127.


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